

Skin Supplements / Skin Boosters / Subcutaneous IV Drip[PN Booster to replenish skin condition] Endran Healer
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[PN Booster to replenish skin condition] Endran Healer
Endran Healer, which utilizes PN, a DNA-derived ingredient obtained from salmon, helps improve the skin environment, and by managing overall skin condition healthily, various skin concerns such as inner dryness, redness, enlarged pores, and reduced elasticity can be alleviated. *VAT separate
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Treatment Details






Features of Endran Healer
1. Rationality derived from the same ingredients
It contains salmon-derived PN ingredients, similar to Rejuran, aiming for skin improvement while reducing the cost burden.
2. Precisely planned treatment process
PN is injected into precise layers and depths tailored to each structure of the skin, helping to achieve efficient improvement.
3. Confirming injection accuracy through the 'embo' phenomenon
Immediately after the procedure, we observe the 'embo' phenomenon with the patient to confirm that the PN ingredient has been injected into the correct position.
4. Consultation and treatment conducted directly by the Head Doctor
After a thorough diagnosis of the skin condition and medical history, we directly perform customized treatments suitable for each individual.
5. Management to minimize irritation and ensure smooth recovery
We conclude the treatment by using a Jwungo modeling mask to comfortably soothe and restore even sensitive skin.
6. Adjusting 'embo' spacing based on skin characteristics of each area
For cheeks and forehead, appropriate spacing is maintained for efficient improvement, while for the eyes and mouth area, injection spacing is adjusted more delicately. We conduct personalized treatments by comprehensively considering factors such as skin thickness, elasticity, and wrinkle direction.
Benefits of Choosing Endran Healer
1. Same Ingredients, Smart Choice
As the patent for PN (Polynucleotide) ingredients in certain products has expired, similar salmon-derived PN products are entering the market.
Endran Healer also contains these same ingredients,
allowing you to consider treatment at a more reasonable cost.
It is a practical PN management solution that offers similar improvement effects while reducing the financial burden.
For those prioritizing cost-effectiveness while considering PN treatments, Endran Healer can be an excellent alternative.
2. Injection Method: More Important Than the Ingredient Itself
Just because a PN ingredient is included does not mean all treatments will yield the same effects.
Endran Healer treatment goes beyond a simple injection process,
focusing on injecting precisely calculated layers and depths, along with the appropriate amount.
We delicately adjust the injection depth for each layer, comprehensively considering skin thickness, degree of damage, and pore structure.
This helps promote healthy changes in the dermis and stimulate collagen production.
3. Confirming Precise Injection Location: We check together via 'embo'.
At our clinic, whether the PN ingredient has been properly injected
is visually confirmed by the medical staff together with the patient.
The 'embo' phenomenon is not merely a temporary reaction but an indicator that the medication has been correctly delivered to the target area.
After the treatment, we take time to check the 'embo' with the patient.
This short 'embo' confirmation process is conducted based on the belief that it can significantly impact the treatment results.
4. 1:1 Consultation and Treatment Directly by the Head Doctor
Instead of a standardized consultation approach, the Head Doctor communicates directly with the patient,
directly assessing skin condition, sensitivity, past treatment experiences, and products being used
from start to finish.
This meticulous diagnosis helps the PN ingredient work more effectively,
and can help prevent unnecessary inflammation or unexpected reactions in advance.
5. Efforts to Minimize Irritation and Ensure Comfortable Recovery
At our clinic, we conclude the PN treatment by including the application of a Jwungo modeling mask as part of the standard procedure.
A Korean herbal complex soothing care is provided to quickly manage skin irritations such as heat sensation, redness, and sensitive reactions.
This management can help pre-regulate the skin's excessive immune response.
Therefore, even those with thin or sensitive skin can receive PN treatment relatively comfortably.
Our clinic focuses on meticulously managing not just the procedure itself, but also the recovery process after the treatment.
6. Customized Embo Interval Design per Area
Endran Hiller treatment is performed with meticulous planning, not only for the injection sites but also for the intervals between each injection point.
For example, for areas like the cheeks or forehead, where the dermal layer is thick and the area is wide,
Since the PN component spreads widely enough with a single injection point, good results can be expected even when treated at 1~1.5cm intervals.
On the other hand, for areas around the eyes or mouth, where the skin is thin and fine wrinkles are densely distributed,
injecting at a finer interval of 0.5cm can be more effective for improving skin texture.
Additionally, if the skin is thin and there are many sunken areas, or
if the skin's texture structure is disrupted due to laser procedures or similar treatments, the treatment plan is adjusted to inject densely even in areas like the cheeks or forehead.
At Kkeuthan Clinic, we meticulously assess the patient's skin thickness and elasticity, wrinkle direction, and desired treatment outcome,
and carefully plan and perform the procedure with a 1:1 customized approach, including the location and intervals of the embo.
Even with the same amount of treatment, the expected results can vary significantly with such customized design.
An approach that considers individual characteristics, rather than a uniform treatment method, is one of Endran Hiller's important features.
Expected Effects of Endran Hiller
1. Promotes collagen and elastin production to improve skin density and elasticity
PN (Polynucleotide), derived from salmon, stimulates fibroblasts in the dermal layer of the skin.
This can promote the production of collagen and elastin.
As a result, skin thickness can increase, fine wrinkles can be reduced, and skin elasticity can improve,
and at the same time, pore improvement effects can also be expected.
2. Restoration of damaged skin barrier and strengthening of self-regeneration
PN components promote the secretion of various growth factors like TGF and FGF, aiding epidermal cell regeneration and contributing to the restoration of the skin barrier.
This can positively impact improving inner dryness, alleviating skin sensitivity, and enhancing the skin's inherent regenerative capacity.
It can be particularly beneficial in aiding the rapid recovery of sensitive skin after laser treatments or chemical peels.
3. Natural Skin Improvement without Being Noticeable
Endran Hiller differs from filler treatments that provide immediate volume or Botox that controls muscles.
This procedure can be expected to enhance the skin's natural regenerative power, leading to smoother skin texture, reduced inner dryness, and improved makeup adherence.
Endran Hiller treatment may be suitable for those who desire natural skin improvement without it being overtly noticeable.
Principle of Endran Hiller Action
1. Skin Structure Improvement through Fibroblast Activation
The key ingredient used in Endran Hiller, PN (Polynucleotide),
is composed of high-purity DNA fragments extracted from salmon. When this ingredient is injected into the skin,
it acts like a skin damage signal, playing a role in activating fibroblasts.
Activated fibroblasts induce the production of skin components such as collagen, elastin, and hyaluronic acid.
This plays a crucial role in increasing skin density and elasticity, thereby restoring a healthy skin structure.
2. Restoration of Skin Self-Regenerative Power through Growth Factor Secretion
When fibroblasts are activated, various types of growth factors, such as TGF-β, are secreted.
TGF-β has the function of promoting collagen synthesis.
FGF is a growth factor that helps with skin regeneration and recovery.
VEGF contributes to improving microcirculation within the skin.
These growth factors create a healthy skin regeneration environment.
This helps the epidermis and skin barrier to naturally regain their resilience.
As a result, skin sensitivity can be reduced, inner dryness is expected to improve, and overall recovery can be enhanced.
3. Enhanced skin elasticity due to improved dermal density
Endran Hiller directly affects the dermis, a crucial component of the skin.
PN aids in the remodeling of the extracellular matrix (ECM), which includes collagen, elastin, hyaluronic acid, and various other substances that make up the dermis.
It can fill the dermal tissue more densely with collagen, hyaluronic acid, and various protein components.
Through this process, the skin's internal density becomes firmer, depressed areas are expected to improve, and skin texture can become more refined, leading to better makeup application.
4. Reduce skin irritation and induce rapid recovery – accompanied by anti-inflammatory effects
Beyond simple skin regeneration, PN can help regulate micro-inflammatory responses within the skin.
Persistent redness
Skin that reacts sensitively to external stimuli
Skin hypersensitivity reactions after laser procedures
Even in these sensitive situations, it can help reduce inflammatory reactions and promote skin recovery.
Thus, Endran Hiller is one of the PN treatments that can be considered relatively comfortably even for sensitive skin types.
Endran Hiller Treatment Process
1. Precise Skin Condition Analysis
Carefully assess skin thickness, elasticity, and sensitivity,
and meticulously plan the appropriate depth and method for PN injection.
2. One-on-One Consultation with Medical Staff
The medical staff will directly identify the skin areas requiring improvement and the overall treatment scope,
and create a customized plan for you.
A treatment plan is established that considers the individual's skin characteristics, not a uniform approach.
3. Anesthetic Cream Application
Since PN is injected directly into the dermis,
a sufficient anesthesia time of about 20 to 30 minutes is provided
to reduce discomfort that may occur during the procedure.
4. Endran Hiller Injection Procedure
PN is precisely injected according to the pre-planned depth and location.
During the procedure, the injection site is immediately confirmed by the 'embossing' phenomenon,
and micro-adjustments are made immediately if necessary to enhance the accuracy of the treatment.
5. Soothing Stage Using Jaungo Modeling Pack
Immediately after the procedure, a Jaungo modeling pack is used
to quickly alleviate skin irritation such as needle marks, redness, and heat sensation.
This helps prevent unnecessary immune responses and ensures a stable skin recovery process.
Endran Hiller Recommended Frequency and Duration of Effects
1. Initial Intensive Treatment (Total of 3 sessions recommended)
Typically, we recommend undergoing a total of 3 sessions, spaced one month apart.
Here's why:
Only when the PN ingredient is accumulated in sufficient quantities in the skin's dermis layer,
can fibroblasts be effectively stimulated and activated,
thereby allowing the collagen reconstruction process to proceed stably.
2. Additional Management for Sustained Treatment Effects
If you wish to maintain the positive changes achieved after your treatment for a longer period,
it is generally recommended to consider retreatment every 6 months to 1 year.
While there may be individual differences depending on skin condition and lifestyle,
after completing the basic 3 treatments, the effects can last approximately 6 to 12 months.
3. How long do the treatment effects last?
After the collagen remodeling process within the skin is stably completed,
improvements in skin texture, elasticity, and density can be maintained for an average of 6 months or more.
However, the duration of maintenance may be shortened in the following cases:
If the skin itself is very thin or already damaged
If you have lifestyle habits that burden the skin, such as smoking or excessive UV exposure
4. When can you expect to feel the treatment effects?
Immediately after treatment: You may experience temporary embossing or mild swelling due to the injections.
Around 1 week: You will start to notice makeup adhering better and your skin feeling smoother.
2-3 weeks: As skin elasticity improves and density increases, a softening effect on fine lines is expected.
After completing all 3 treatments: The positive changes in the internal structure of the skin will become more pronounced, leading to an overall improvement in skin condition.
What is the typical pain level during Endran Filler treatment?
Most individuals experience a tolerable level of stinging.
Since the PN ingredient is directly injected into the dermal layer of the skin, it is not a completely painless procedure;
however, anesthetic cream is applied for a sufficient period before the procedure, allowing most patients to complete the treatment comfortably.
Pain Level by Treatment Area
Areas such as the cheeks, forehead, and around the mouth tend to experience less pain.
Around the eyes, bridge of the nose, and chin, a momentary sting may be felt during the procedure.
In areas with widely distributed pores, a slightly heavy pressure sensation may occur during drug injection.
Efforts to Minimize Pain During Treatment
We ensure sufficient application time for anesthetic cream to raise the pain threshold.
During the procedure, the medication is injected slowly in small, divided amounts, rather than a large amount at once.
We continuously monitor and adjust to the patient's pain level in real-time during the procedure.
After the procedure, we provide soothing pack management to help your skin feel comfortable.
Endran Filler treatment may be considered for those who:
1. Are concerned about noticeable fine lines
Especially when fine lines are densely present in various facial areas such as around the eyes, cheeks, and mouth,
it is suitable for those who feel burdened by lifting procedures or fillers and desire a more natural approach to wrinkle improvement.
2. Have highly sensitive skin that tends to redden easily
If you have sensitive skin that reacts easily to changes in cosmetics or frequently experiences flushing,
this treatment can be considered if you wish to restore weakened skin barrier function and regain your skin's natural health.
3. Those experiencing severe dryness deep within the skin and makeup caking
This treatment can help if your skin appears oily on the surface but feels dry and tight underneath, leading to makeup caking.
It may be suitable for dehydrated skin where deep skin tightness persists even with thorough moisturizing.
4. Those who have lost skin vitality due to frequent treatments
This applies to cases where repeated treatments, such as laser or chemical peels, have made the skin thinner and more sensitive.
This can be a suitable treatment for those looking to restore their skin's natural recovery ability.
5. Those who desire skin density and a smooth texture
This refers to a condition where the skin has generally lost its firmness and feels somewhat loose or saggy due to reduced elasticity.
It can be beneficial if you notice sagging skin around the cheekbones or cheeks, along with an uneven skin texture.
Embossing After Endran Healer Treatment
After Endran Healer treatment, small, temporary bumps (embossing) may be observed at the injection site.
This is a positive sign indicating that the active ingredients have been properly injected into the dermal layer.
The appearance of small, raised bumps on the skin is a normal reaction, signifying that you can anticipate the treatment's positive effects.
In most cases, these bumps (embossing) will naturally subside within 1-2 days.
If your skin is thin or dry, the bumps may last for about 2-3 days; for sensitive areas around the eyes or mouth, they might persist for up to 4 days.
Occasionally, the bumps may remain for 5 to 7 days or even longer, but
there's no need to worry if you don't experience symptoms like pain, warmth, or severe redness.
In such cases, it could actually be a positive sign that the medication is being absorbed slowly and working for a longer duration.
Post-Treatment Precautions
- After the treatment, you may experience bumps, redness, and mild pain at the injection site for about 2-3 days.
- Bruising, tiny needle marks at the injection site, and swelling may persist for about 1 to 2 weeks after the treatment.
- For about one week after treatment, please avoid alcohol and smoking. It's also recommended to refrain from saunas, swimming pools, and strenuous exercise to minimize skin irritation.
- Adequate moisturizing care is important to soothe your skin after the treatment. When going out, it is highly recommended to meticulously apply sunscreen.
Procedure Flow
첫 상담부터 마무리까지의 실제 진행 순서를 확인하세요.
- 01
Step 01: Cleanse your face thoroughly by yourself.
- 02
Step 02: Check your current skin condition.
- 03
Step 03: Proceed with personalized consultation.
- 04
Step 04: Apply anesthetic cream.
- 05
Step 05: Begin the procedure.
- 06
Step 06: Soothe with Jaungo Modeling Pack.
- 07
Step 07: Finish with regenerating cream.
시술 기본정보
시술 시간, 마취, 회복, 유지기간을 한 번에 확인하세요.
TIME
30 minutes ~ 1 hour
ANESTHESIA
Anesthetic cream (15~30 minutes)
RECOVERY
Immediate return to daily life
DURATION
3~6 months
Ideal For
One Fine Difference makes real results.
- KKEUT POINT 01
Those whose skin feels dry, parched, and rough due to dryness
- KKEUT POINT 02
Those who expect improvement in fine wrinkles and enhanced skin elasticity
Q&A
고객님들이 가장 많이 물어보시는 내용을 모았습니다.
Is this treatment similar to Rejuran?
Endran Healer is a drug injection treatment containing polynucleotide (PN) components, similar to Rejuran. Particularly, positive effects can be expected in improving moisture retention in dry skin.
What is the appropriate treatment interval?
Generally, we recommend a total of 3 treatments at one-month intervals.
Is it possible to use a device for injection treatments?
If you are concerned about pain, the treatment can be performed using a Dermashine device.
Cautions
Results = Treatment × Aftercare. Please follow the notes below.
The treated area may temporarily swell or redden, and there may be minor bleeding, bruising, or slight bumps like embossing. These reactions usually subside naturally within about 1 week.
For about 1 week after the procedure, it is advisable to refrain from alcohol and smoking, and to avoid visiting saunas or swimming pools, as well as strenuous physical activities.
Avoid excessive rubbing or stimulating the treated area.
It is advisable not to use scrub products or exfoliants that can irritate the skin for about 1 week after the procedure.
